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Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
GDC-0941
Highlight These Spots (
fill
):
GDC-0941|AAK1|9100
GDC-0941|CAMK1|4700
GDC-0941|CAMK1G|6800
GDC-0941|CLK1|1100
GDC-0941|CLK2|600
GDC-0941|CLK4|1500
GDC-0941|CSNK1D|1200
GDC-0941|CSNK1E|1200
GDC-0941|CSNK2A2|2400
GDC-0941|DAPK1|4000
GDC-0941|DAPK3|1800
GDC-0941|DYRK1B|3800
GDC-0941|DYRK2|7600
GDC-0941|EPHB6|1600
GDC-0941|FLT3|2600
GDC-0941|GAK|2700
GDC-0941|HIPK1|1100
GDC-0941|HIPK2|520
GDC-0941|HIPK3|600
GDC-0941|HIPK4|5000
GDC-0941|ICK|9300
GDC-0941|IRAK3|1700
GDC-0941|JAK1(JH2domain-pseudokinase)|430
GDC-0941|JNK1|1500
GDC-0941|JNK2|1800
GDC-0941|JNK3|560
GDC-0941|MELK|5700
GDC-0941|MTOR|200
GDC-0941|MYLK4|780
GDC-0941|PCTK1|1100
GDC-0941|PCTK3|4600
GDC-0941|PIK3C2B|130
GDC-0941|PIK3C2G|300
GDC-0941|PIK3CA|1.1
GDC-0941|PIK3CB|16
GDC-0941|PIK3CD|5
GDC-0941|PIK3CG|48
GDC-0941|PLK4|2600
GDC-0941|RIOK2|670
GDC-0941|RSK2(Kin.Dom.1-N-terminal)|3000
GDC-0941|RSK4(Kin.Dom.1-N-terminal)|5400
GDC-0941|STK16|1100
GDC-0941|TTK|4300
GDC-0941|TYK2(JH2domain-pseudokinase)|1800
GDC-0941|YSK4|4000
GDC-0941|AAK1
GDC-0941|CAMK1
GDC-0941|CAMK1G
GDC-0941|CLK1
GDC-0941|CLK2
GDC-0941|CLK4
GDC-0941|CSNK1D
GDC-0941|CSNK1E
GDC-0941|CSNK2A2
GDC-0941|DAPK1
GDC-0941|DAPK3
GDC-0941|DYRK1B
GDC-0941|DYRK2
GDC-0941|EPHB6
GDC-0941|FLT3
GDC-0941|GAK
GDC-0941|HIPK1
GDC-0941|HIPK2
GDC-0941|HIPK3
GDC-0941|HIPK4
GDC-0941|ICK
GDC-0941|IRAK3
GDC-0941|JAK1(JH2domain-pseudokinase)
GDC-0941|JNK1
GDC-0941|JNK2
GDC-0941|JNK3
GDC-0941|MELK
GDC-0941|MTOR
GDC-0941|MYLK4
GDC-0941|PCTK1
GDC-0941|PCTK3
GDC-0941|PIK3C2B
GDC-0941|PIK3C2G
GDC-0941|PIK3CA
GDC-0941|PIK3CB
GDC-0941|PIK3CD
GDC-0941|PIK3CG
GDC-0941|PLK4
GDC-0941|RIOK2
GDC-0941|RSK2(Kin.Dom.1-N-terminal)
GDC-0941|RSK4(Kin.Dom.1-N-terminal)
GDC-0941|STK16
GDC-0941|TTK
GDC-0941|TYK2(JH2domain-pseudokinase)
GDC-0941|YSK4
GDC-0941|AAK1|9100
GDC-0941|CAMK1|4700
GDC-0941|CAMK1G|6800
GDC-0941|CLK1|1100
GDC-0941|CLK2|600
GDC-0941|CLK4|1500
GDC-0941|CSNK1D|1200
GDC-0941|CSNK1E|1200
GDC-0941|CSNK2A2|2400
GDC-0941|DAPK1|4000
GDC-0941|DAPK3|1800
GDC-0941|DYRK1B|3800
GDC-0941|DYRK2|7600
GDC-0941|EPHB6|1600
GDC-0941|FLT3|2600
GDC-0941|GAK|2700
GDC-0941|HIPK1|1100
GDC-0941|HIPK2|520
GDC-0941|HIPK3|600
GDC-0941|HIPK4|5000
GDC-0941|ICK|9300
GDC-0941|IRAK3|1700
GDC-0941|JAK1(JH2domain-pseudokinase)|430
GDC-0941|JNK1|1500
GDC-0941|JNK2|1800
GDC-0941|JNK3|560
GDC-0941|MELK|5700
GDC-0941|MTOR|200
GDC-0941|MYLK4|780
GDC-0941|PCTK1|1100
GDC-0941|PCTK3|4600
GDC-0941|PIK3C2B|130
GDC-0941|PIK3C2G|300
GDC-0941|PIK3CA|1.1
GDC-0941|PIK3CB|16
GDC-0941|PIK3CD|5
GDC-0941|PIK3CG|48
GDC-0941|PLK4|2600
GDC-0941|RIOK2|670
GDC-0941|RSK2(Kin.Dom.1-N-terminal)|3000
GDC-0941|RSK4(Kin.Dom.1-N-terminal)|5400
GDC-0941|STK16|1100
GDC-0941|TTK|4300
GDC-0941|TYK2(JH2domain-pseudokinase)|1800
GDC-0941|YSK4|4000
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
GDC-0941
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
GDC-0941
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\804_pbptdteazizm1jj0svmtwrhy\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
GDC-0941
Legend
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Size:
Select Size
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medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
CLK1
CLK2
CLK4
CSNK1D
CSNK1E
CSNK2A2
DAPK3
EPHB6
FLT3
FLT3
GAK
HIPK1
HIPK2
HIPK3
IRAK3
JAK1(JH2domain-pseudokinase)
JNK1
JNK2
JNK3
MTOR
MYLK4
PCTK1
PIK3C2B
PIK3C2G
PIK3CA
PIK3CA
PIK3CB
PIK3CD
PIK3CG
PLK4
RIOK2
STK16
TYK2(JH2domain-pseudokinase)
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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